Soul Eater

Here we have Soul Eater, a shounen anime produced by Bones (Wolf's Rain, Full Metal Alchemist, Ouran High School Host Club) that came out in 2008. Although the manga and anime take quite different routes, this is based solely on the anime. Set in the fantastical Death City, Soul Eater focuses on the Shibusen Academy, where students both work together and compete in order to turn their partners - boys and girls that can turn into various different weapons - into world-class Death Scythes. I blasted through all 51 episodes in about a week, and let me tell you, this does not make for hard watching. 

The first few episodes start off as prequels for the main seven characters - three 'Meisters/Technicians' and their 'Weapons'. These episodes are ones that I found to be somewhat disjointed, and to be honest I probably would have given up on the anime after 4 episodes or so if it wasn't for aforementioned pally. Swiftly afterwards, once the main characters start to interact together, I was hooked. And shortly after that when the frankly ingenious support characters were introduced and fleshed out, I was manic about it to the point where I was screaming in outrage at the screen if any other character DARED to so much as harm a hair on their heads.

Easy to watch and a great mix of creepy, surreal and fun, and the downright enjoyment I experienced with this show was extraordinary. I thoroughly recommend this to anyone who enjoys Full Metal Alchemist or Gintama - or, for that matter, any shounen manga/anime.